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           Vitamin B12

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Vitamin B12: Vitamin B12 is critical to building DNA and RNA, the maintenance of the nervous system, fatty acid synthesis, homocysteine metabolism and energy production. It is estimated that B12 deficiency occurs in 10-15% of the elderly and 30% of those who have had gastric surgery.

Toxicity: There are occasional reports of hypersensitivity reactions in patients receiving parenteral doses of B12. Oral B12 is tolerated well even in very high doses. 

Tolerable upper limits: None reported.

Drug Interactions: Anitbiotics, cholestyramine, colchecine, proton pump inhibitors, H2 blockers and metformin may decrease B12 levels.



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Last modified: June 04, 2005