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           Thiamin (B1)

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Thiamin (B1): Thiamin is essential in carbohydrate and branch chain amino acid metabolism. Classical deficiency is called berberi, which may be manifested by peripheral neuropathy, congestive heart failure, lactic acidosis and central nervous system changes. It may be seen in alcoholics, malabsorption states, patients with HIV, thyrotoxicosis, and patients on loop diuretics (e.g. furosamide).

Toxicity: None reported.

Tolerable Upper Limits: Not established.

Drug interactions: Loop diuretics, sulfites, tea, coffee and decaffinated coffee may all decrease thiamin.

 

 

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Last modified: June 04, 2005